The UK Primary Care Research Resource

Primary Care Research.
Done Properly.

The definitive resource for clinical research in UK general practice. Guidance for pharmaceutical sponsors, GP practices, and researchers navigating the primary care research landscape.

8M
Patients across PCRA practices
100+
GP practices across the network
2 wks
Record time to first patient enrolled
250
Trial posters placed in 4 days

Research that works for everyone

Whether you're a pharmaceutical sponsor, a GP practice ready to deliver research, or a researcher navigating the primary care landscape โ€” this is your resource.

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Pharmaceutical & Medtech Sponsors

Run faster, leaner clinical trials and real-world evidence studies in UK GP practices. Access 8 million patients through a single, organised network partner.

Find out more
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GP Practices & PCNs

Become a research-active practice. Access NIHR funding, build your team's capability, and generate income while contributing to evidence that transforms patient care.

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Researchers & Academics

Navigate the regulatory landscape, access real-world primary care data, and understand the infrastructure available for primary care research in England.

Explore resources

Everything you need to know

Five comprehensive pillar guides covering every aspect of primary care research in the UK.

01

What Is Primary Care Research?

A complete introduction to clinical research in GP settings โ€” types, funders, regulators, and why primary care matters.

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02

How to Set Up a GP Clinical Trial Site

Step-by-step guidance for practices wanting to become research-active, from GCP training to NIHR registration.

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03

MHRA, HRA & REC Explained

Plain-English guide to the regulatory framework for clinical research in general practice.

Read the guide
04

Real World Evidence in Primary Care

Why GP data is the richest source of real-world evidence in the NHS and how it's shaping drug development.

Read the guide
05

Commercial Research in General Practice

What pharmaceutical and medtech sponsors need to know before partnering with GP practices for clinical trials.

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News & analysis

Expert commentary from practising GPs and research leaders on the issues shaping primary care research.

Case Study

The Power of Primary Care Networks: 250 Posters in 4 Days

When a sponsor needed rapid patient awareness for a clinical trial, PCRA activated its network and placed 250 recruitment posters across member practices in just four days.

Dr Daphne Hazell ยท April 2026
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Funding & Policy

New NIHR Funding Streams for Primary Care Research โ€” What GP Practices Need to Know

The NIHR has launched two major new funding streams for 2026/27 that could provide your practice with substantial infrastructure support to deliver research.

Dr Daphne Hazell ยท April 2026
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Workforce

The GP with Extended Role in Clinical Research โ€” A Career-Defining Opportunity

As NIHR doubles down on primary care research delivery, the role of the research-focused GP has never been more professionally significant โ€” or financially rewarding.

Dr Daphne Hazell ยท April 2026
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Ready to run a trial in primary care?

The Primary Care Research Alliance delivers commercial and NIHR research across 100+ GP practices with 8 million patients.

Talk to PCRA โ†’